1. Sphingomyelinase D Activity in Sicarius tropicus Venom: Toxic Potential and Clues to the Evolution of SMases D in the Sicariidae Family. Lopes PH, Fukushima CS, Shoji R, Bertani R, Tambourgi DV. Toxins (Basel). 2021 Apr 1;13(4):256. doi: 10.3390/toxins13040256. PMID: 33916208; PMCID: PMC8066738.

2. Silva de França F, Villas-Boas IM, Cogliati B, Woodruff TM, Reis EDS, Lambris JD, Tambourgi DV. C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera. Front Immunol. 2021 Apr 15;12:652242. doi: 10.3389/fimmu.2021.652242. PMID: 33936074; PMCID: PMC8082402.

3. Searching for the toxic potential of Loxosceles amazonica and Loxosceles willianilsoni spiders' venoms. Lopes PH, Fukushima CS, Shoji R, Bertani R, Tambourgi DV. Toxicon. 2021 Feb;191:1-8. doi: 10.1016/j.toxicon.2020.12.006. Epub 2020 Dec 25. PMID: 33347860.

4. Integrative multiomics analysis of Premolis semirufa caterpillar venom in the search for molecules leading to a joint disease. Pidde G, Nishiyama MY, de Oliveira UC, Villas-Boas IM, Paes-Leme AF, Junqueira-de-Azevedo IL, Marques-Porto R, Squaiella-Baptistão CC, Tambourgi DV. Sci Rep. 2021 Jan 21;11(1):1995. doi: 10.1038/s41598-020-79769-y. PMID: 33479267; PMCID: PMC7820220.

5. Heluany CS, Donate PB, Schneider AH, Fabris AL, Gomes RA, Villas-Boas IM, Tambourgi DV, Silva TAD, Trossini GHG, Nalesso G, Silveira ELV, Cunha FQ, Farsky SHP. Hydroquinone Exposure Worsens Rheumatoid Arthritis through the Activation of the Aryl Hydrocarbon Receptor and Interleukin-17 Pathways. Antioxidants (Basel). 2021 Jun 7;10(6):929. doi:10.3390/antiox10060929. PMID: 34200499; PMCID: PMC8229175.

6. Bothrops lanceolatus snake (Fer-de-lance) venom triggers inflammatory mediators' storm in human blood. Silva de França F, Gabrili JJM, Mathieu L, Burgher F, Blomet J, Tambourgi DV. Arch Toxicol. 2021 Mar;95(3):1129-1138. doi: 10.1007/s00204-020-02959-0. Epub 2021 Jan 4. PMID: 33398417.

7. The Crotoxin:SBA-15 Complex Down-Regulates the Incidence and Intensity of Experimental Autoimmune Encephalomyelitis Through Peripheral and Central Actions. Sant'Anna MB, Giardini AC, Ribeiro MAC, Lopes FSR, Teixeira NB, Kimura LF, Bufalo MC, Ribeiro OG, Borrego A, Cabrera WHK, Ferreira JCB, Zambelli VO, Sant'Anna OA, Picolo G. Front Immunol. 2020 Oct 28;11:591563. doi: 10.3389/fimmu.2020.591563. PMID: 33193433; PMCID: PMC7655790.

8. Sphingomyelinases D From Loxosceles Spider Venoms and Cell Membranes: Action on Lipid Rafts and Activation of Endogenous Metalloproteinases. Lopes PH, van den Berg CW, Tambourgi DV. Front Pharmacol. 2020 May 13;11:636. doi: 10.3389/fphar.2020.00636. PMID: 32477123; PMCID: PMC7237637.

9. Serological evidence of Toxoplasma gondii infection as potential risk for the development of lepromatous leprosy in an endemic area for both neglected tropical diseases in Brazil. Oliveira LRP, Martins LM, Souza RDC, Scheidegger de Castro Y, Nascimento LS, da Silva JA, Nahn Junior EP, da Silva WD, Peixoto-Rangel AL. Infect Dis Poverty. 2020 Feb 13;9(1):19. doi: 10.1186/s40249-020-0636-3. PMID: 32051036; PMCID: PMC7017566.

10. Self-Assembled Cationic-Covered Nanoemulsion as A Novel Biocompatible Immunoadjuvant for Antiserum Production Against Tityus serrulatus Scorpion Venom. Medeiros ASA, Torres-Rêgo M, Lacerda AF, Rocha HAO, Egito ESTD, Cornélio AM, Tambourgi DV, Fernandes-Pedrosa MF, da Silva-Júnior AA. Pharmaceutics. 2020 Sep 29;12(10):927. doi:10.3390/pharmaceutics12100927. PMID: 33003322; PMCID:PMC7599857.

11. P-MAPA, a Fungi-Derived Immunomodulatory Compound, Induces a Proinflammatory Response in a Human Whole Blood Model. Gonçalves MT, Squaiella-Baptistão CC, Pidde G, Lopes PH, da Silva Nunes I, Tambourgi DV. Mediators Inflamm. 2020 Nov 24;2020:8831389. doi: 10.1155/2020/8831389. PMID: 33299378; PMCID: PMC7707968.

12. Human Chondrocyte Activation by Toxins From Premolis semirufa, an Amazon Rainforest Moth Caterpillar: Identifying an Osteoarthritis Signature. Villas-Boas IM, Pidde G, Lichtenstein F, Ching ATC, Junqueira-de-Azevedo ILM, DeOcesano-Pereira C, Madureira Trufen CE, Chudzinski-Tavassi AM, Morais KLP, Tambourgi DV. Front Immunol. 2020 Sep 18;11:2191. doi:10.3389/fimmu.2020.02191. PMID: 33072083; PMCID: PMC7531038.

13. Evaluation of NDEL1 oligopeptidase activity in blood and brain in an animal model of  chizophrenia: effects of psychostimulants and antipsychotics. Nani JV, Lee RS, Yonamine CM, Sant'Anna OA, Juliano MA, Gadelha A, Mari JJ, Hayashi MAF. Sci Rep. 2020 Oct 28;10(1):18513. doi: 10.1038/s41598-020-75616-2. PMID: 33116174; PMCID: PMC7595172.

14. Cytotoxic and genotoxic effects on human keratinocytes triggered by sphingomyelinase D from Loxosceles venom. da Silva MS, Lopes PH, Elias MC, Tambourgi DV. Arch Toxicol. 2020 Oct;94(10):3563-3577. doi: 10.1007/s00204-020-02830-2. Epub 2020 Jun 30. PMID: 32607614.

15. Bitis arietans Snake Venom Induces an Inflammatory Response Which Is Partially Dependent on Lipid Mediators. Megale AAA, Portaro FC, Da Silva WD.Toxins (Basel). 2020 Sep 14;12(9):594. doi: 10.3390/toxins12090594. PMID: 32937985; PMCID: PMC7551280.

16. A Kunitz-type peptide from Dendroaspis polylepis venom as a simultaneous inhibitor of serine and cysteine proteases. Kodama RT, Kuniyoshi AK, da Silva CCF, Cajado-Carvalho D, Duzzi B, Mariano DC, Pimenta DC, Borges R, da Silva WD, Portaro FCV. J Venom Anim Toxins Incl Trop Dis. 2020 Oct 7;26:e20200037. doi: 10.1590/1678-9199-JVATITD-2020-0037. PMID: 33088285; PMCID: PMC7546081.

17. Clinical aspects, diagnosis and management of Loxosceles spider envenomation: literature and case review. Lopes PH, Squaiella-Baptistão CC, Marques MOT, Tambourgi DV. Arch Toxicol. 2020 May;94(5):1461-1477. doi:10.1007/s00204-020-02719-0. Epub 2020 Mar 30. PMID: 32232511.

18. Tityus serrulatus Scorpion Venom Induces Apoptosis in Cervical Cancer Cell Lines. Bernardes-Oliveira E, Farias KJS, Gomes DL, de Araújo JMG, da Silva WD, Rocha HAO, Donadi EA, Fernandes-Pedrosa MF, Crispim JCO. Evid Based Complement Alternat Med. 2019 Jun 23;2019:5131042. doi: 10.1155/2019/ 5131042. PMID: 31341494; PMCID: PMC6612397.

19. Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation. Silva-de-França F, Villas-Boas IM, Serrano SMT, Cogliati B, Chudzinski SAA, Lopes PH, Kitano ES, Okamoto CK, Tambourgi DV. PLoS Negl Trop Dis. 2019 Jan 18;13(1):e0007017. doi: 10.1371/journal.pntd.0007017. PMID: 30657756; PMCID: PMC6338361.

20. Complement System Inhibition Modulates the Pro-Inflammatory Effects of a Snake Venom Metalloproteinase. Luchini LSG, Pidde G, Squaiella-Baptistão CC, Tambourgi DV. Front Immunol. 2019 May 22;10:1137. doi: 10.3389/fimmu.2019.01137. Erratum in: Front Immunol. 2019 Jul 03;10:1539. PMID: 31231362; PMCID: PMC6558526.

21. Antigenic and physicochemical characterization of Hepatitis B surface protein under extreme temperature and pH conditions. Lopes JLS, Oliveira DCA, Utescher CLA, Quintilio W, Tenório ECN, Oliveira CLP, Fantini MCA, Rasmussen MK, Bordallo HN, Sant'Anna OA, Botosso VF. Vaccine. 2019 Oct 8;37(43):6415-6425. doi: 10.1016/j.vaccine.2019.09.005. Epub 2019 Sep 10. PMID: 31519445.

22. Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism. Lopes PH, Murakami MT, Portaro FCV, Mesquita Pasqualoto KF, van den Berg C, Tambourgi DV. J Enzyme Inhib Med Chem. 2019 Dec;34(1):310-321. doi: 10.1080/14756366.2018.1546698. PMID: 30734604; PMCID: PMC6327989.

23. 3D visualisation of hepatitis B vaccine in the oral delivery vehicle SBA-15. Rasmussen MK, Kardjilov N, Oliveira CLP, Watts B, Villanova J, Botosso VF, Sant'Anna OA, Fantini MCA, Bordallo HN. Sci Rep. 2019 Apr 15;9(1):6106. doi: 10.1038/s41598-019-42645-5. PMID: 30988384; PMCID: PMC6465313.

24. Venomous caterpillars: From inoculation apparatus to venom composition and envenomation.  Villas-Boas IM, Bonfá G, Tambourgi DV. Toxicon. 2018 Oct;153:39-52. doi: 10.1016/j.toxicon.2018.08.007. Epub 2018 Aug 24. PMID: 30145232.

25. Venom from Bothrops lanceolatus, a Snake Species Native to Martinique, Potently Activates the Complement System. Delafontaine M, Villas-Boas IM, Pidde G, van den Berg CW, Mathieu L, Blomet J, Tambourgi DV. J Immunol Res. 2018 Jul 15;2018:3462136. doi:10.1155/2018/3462136. PMID: 30116749; PMCID: PMC6079423.

26. The history of antivenoms development: Beyond Calmette and Vital Brazil. Squaiella -Baptistão CC, Sant'Anna OA, Marcelino JR, Tambourgi DV. Toxicon. 2018 Aug;150:86-95. doi: 10.1016/j.toxicon.2018.05.008. Epub 2018 May 17. PMID: 29778595.

27. The Ex vivo Eye Irritation Test (EVEIT) model as a mean of improving venom ophthalmia understanding. Delafontaine M, Panfil C, Spöler F, Kray S, Burgher F, Mathieu L, Blomet J, Schrage NF, Tambourgi DV. Toxicon. 2018 Aug;150:253-260. doi:10.1016/j.toxicon.2018.06.061. Epub 2018 Jun 8. PMID: 29890230.

28. Squaiella-Baptistão CC, Magnoli FC, Marcelino JR, Sant'Anna OA, Tambourgi DV. Quality of horse F(ab')₂ antitoxins and anti-rabies immunoglobulins: protein content and anticomplementary activity. J Venom Anim Toxins Incl Trop Dis. 2018 Jun 18;24:16. doi: 10.1186/s40409-018-0153-z. PMID: 29946337; PMCID: PMC6006770.

29. Soares KSR, Gláucia-Silva F, Daniele-Silva A, Torres-Rêgo M, Araújo NK, Menezes YAS, Damasceno IZ, Tambourgi DV, da Silva-Júnior AA, Fernandes-Pedrosa MF. Antivenom Production against Bothrops jararaca and Bothrops erythromelas Snake Venoms Using Cross-Linked Chitosan Nanoparticles as an Immunoadjuvant. Toxins (Basel). 2018 Apr 16;10(4):158. doi: 10.3390/toxins10040158. PMID: 29659491; PMCID: PMC5923324.

30. Snake venoms from Angola: Intra-specific variations and immunogenicity. Oliveira PRS, França FS, Villas Boas IM, Rocha MMTD, Sant'Anna SS, Bastos ML, Tambourgi DV. Toxicon. 2018 Jun 15;148:85-94. doi: 10.1016/j.toxicon.2018.04.013. Epub 2018 Apr 16. PMID: 29673703.

31. Persistence and Intra-Host Genetic Evolution of Zika Virus Infection in Symptomatic Adults: A Special View in the Male Reproductive System. Oliveira DBL, Durigon GS, Mendes ÉA, Ladner JT, Andreata-Santos R, Araujo DB, Botosso VF, Paola ND, Neto DFL, Cunha MP, Braconi CT, Alves RPS, Jesus MR, Pereira LR, Melo SR, Mesquita FS, Silveira VB, Thomazelli LM, Favoretto SR, Almonfrey FB, Abdulkader RCRM, Gabrili JM, Tambourgi DV, Oliveira SF, Prieto K, Wiley MR, Ferreira LCS, Silva MV, Palacios GF, Zanotto PMA, Durigon EL. Viruses. 2018 Nov 7;10(11):615. doi: 10.3390/v10110615. PMID: 30405055; PMCID:PMC6267439.

32. Loxosceles venom Sphingomyelinase D activates human blood leukocytes: Role of the complement system. Manzoni-de-Almeida D, Squaiella-Baptistão CC, Lopes PH, van den Berg CW, Tambourgi DV. Mol Immunol. 2018 Feb;94:45-53. doi: 10.1016/j.molimm.2017.12.009. Epub 2017 Dec 16. PMID: 29257998.

33. Leptospira interrogans outer membrane protein LipL21 is a potent inhibitor of neutrophil myeloperoxidase. Vieira ML, Teixeira AF, Pidde G, Ching ATC, Tambourgi DV, Nascimento ALTO, Herwald H. Virulence. 2018 Jan 1;9(1):414-425. doi: 10.1080/21505594.2017.1407484. PMID: 29235397; PMCID: PMC5955187.

34. Kn-Ba: a novel serine protease isolated from Bitis arietans snake venom with fibrinogenolytic and kinin-releasing activities. Megale ÂAA, Magnoli FC, Kuniyoshi AK, Iwai LK, Tambourgi DV, Portaro FCV, da Silva WD. J Venom Anim Toxins Incl Trop Dis. 2018 Dec 13;24:38. doi: 10.1186/s40409-018-0176-5. PMID: 30564275; PMCID: PMC6293559.

35. Comparison of two Jatropha species (Euphorbiaceae) used popularly to treat snakebites in Northeastern Brazil: Chemical profile, inhibitory activity against Bothrops erythromelas venom and antibacterial activity. Félix-Silva J, Gomes JAS, Fernandes JM, Moura AKC, Menezes YAS, Santos ECG, Tambourgi DV, Silva-Junior AA, Zucolotto SM, Fernandes-Pedrosa MF. J Ethnopharmacol. 2018 Mar 1;213:12-20. doi: 10.1016/j.jep.2017.11.002. Epub 2017 Nov 4. PMID: 29113958.

36. A biotechnological approach to immunotherapy: Antivenom against Crotalus durissus cascavella snake venom produced from biodegradable nanoparticles. Gláucia-Silva F, Torres-Rêgo M, Rocha Soares KS, Damasceno IZ, Tambourgi DV, Silva-Júnior AAD, Fernandes-Pedrosa MF. Int J Biol Macromol. 2018 Dec;120(Pt B):1917-1924. doi: 10.1016/j.ijbiomac.2018.09.203. Epub 2018 Oct 1. PMID: 30287370.

37. Tetracycline Reduces Kidney Damage Induced by Loxosceles Spider Venom. Okamoto CK, van den Berg CW, Masashi M, Gonçalves-de-Andrade RM, Tambourgi DV. Toxins (Basel). 2017 Mar 2;9(3):90. doi: 10.3390/toxins9030090. PMID: 28257106; PMCID: PMC5371845.

38. Inhibition of local effects induced by Bothrops erythromelas snake venom: Assessment of the effectiveness of Brazilian polyvalent bothropic antivenom and aqueous leaf extract of Jatropha gossypiifolia. Félix-Silva J, Gomes JA, Xavier-Santos JB, Passos JG, Silva-Junior AA, Tambourgi DV, Fernandes-Pedrosa MF. Toxicon. 2017 Jan;125:74-83. doi:10.1016/j.toxicon.2016.11.260. Epub 2016 Nov 25. PMID: 27890774.

39. Enzymatic and Pro-Inflammatory Activities of Bothrops lanceolatus Venom: Relevance for Envenomation. Delafontaine M, Villas-Boas IM, Mathieu L, Josset P, Blomet J, Tambourgi DV. Toxins (Basel). 2017 Aug 7;9(8):244. doi: 10.3390/toxins9080244. PMID: 28783135; PMCID: PMC5577578.